Services

Microbial Fermentation

AbbVie Contract Manufacturing offers world-class fermentation services based on more than 60 years of leadership in fermentation.

Let's Talk ›
Hero_Wave2.png

Scroll

All Things Great and Small

A partner like no other.

The North Chicago site is a unique asset in North America with more than 3 million liters of aerobic fermentation capacity and a variety of downstream capabilities to support numerous types of organisms.  These capabilities combined with a pilot plant that mimics all of the commercial scale capabilities enables AbbVie to successfully deliver all of your project needs from process development to commercial manufacturing. 

Download Cut Sheet ›

Types of Products

  • Small molecule API
  • Large molecule API administered orally
  • Bulk food ingredients
  • Semi-synthetic API’s

Types of Organisms

  • GMO & non-GMO
  • Streptomyces
  • e. coli
  • Fungi
  • Bacillus
  • Yeast

Pilot Plant

  • Preparation of R&D, master and working cell banks
  • Inoculum process development
  • Fermentation process optimization at 55 and 500 L scale
  • Downstream process optimization and characterization

Microbial Fermentation Manufacturing

  • 3,000 m3 fermentation capacity
  • Fermenter working volumes from 10 to 100 m3
  • Downstream capabilities including microfiltration, centrifugation, extraction, ultrafiltration, chromatography, crystallization and fluid-bed drying
  • Bulk packaging of liquids into totes and tanker trucks and dried solids into drums

Analytical

  • HPLC, GC, GC-MS, LC-MS
  • Spectrophotometry
  • Wet chemistry including LOD, pH, heavy metals
  • Stability testing
  • On-site microbial lab including bioburden

An AbbVie CMO representative is eager to talk to you.

AbbVie CMO is a seasoned partner for all your contract manufacturing needs. Let’s start a conversation today. The future is a click away.

Let's Talk ›

Why a Robust Quality Culture is Central to Patient Safety

Load More

Top Four Things to Consider when Looking for a CDMO to Maximize Drug Substance Utilization

Load More

CMO as Partners for ADC Process Development, Scale-up, and Optimization

Load More

Insight Delivered

Sign-up for our email service to get CMO insights and updates right to your digital doorstep.

There was a problem submitting the form. Please try again later.
required

The categories of personal information collected in this form include name, company, and contact information. The personal information collected will be used for exploratory discussions on contract manufacturing, marketing and to perform research and analytics. For more information about the categories of personal information collected by AbbVie and the purposes for which AbbVie uses personal information, visit https://privacy.abbvie.

Thank you for subscribing!

You’ve been added to our list and will hear from us soon.