- Flexible scales from boutique to large scale
- Production network delivers broad flexibility in scale and location
- Solution and consultative partnerships from development through commercial term
- Established wide network of commercial assets to accelerate speed to market
AbbVie’s Experience
Unique Capabilities
- Potent (<1μg/m3) manufacturing and storage
- Offer End to End manufacturing from API to bulk oral solid dose to finished Drug Product packaging
- Extensive controlled temperature warehousing capability (2–8˚C API and Drug Product)
- Hot melt extrusion for difficult to formulate compounds/bioavailability enhancement
Oral Solid Dose Manufacturing
Blending
- V-blenders (2ft3–150ft3 scale)
- Bin blenders
Granulation & Drying Capabilities
- Roller Compaction
- High Shear granulation (75L, 300L and 1,200L)
- Spray granulation (400L–1,100L)
- Melt granulation (18mm–70mm screw size)
- Fluid Bed Drying
- Tray Drying
Milling capabilities
- Impact milling
- Screen milling
- Separation
Compression Capabilities
- Single layer
- Multi-layer
- Mini tab
Coating Capabilities
- Tablet coating
- Particle coating
- Active coating
Encapsulation Capabilities
- Granule filled
- Liquid filled (hard gelatin)
- Mini tab filled
- Over encapsulation
Packaging Capabilities
- Blisters
- Bottles
- Sachets/Sticks
- Wallets
Oral Liquid Manufacturing & Finishing
- Formulation
- Syrups/Suspensions/Solutions
- Bottle filling (15mL–500mL)