Active Pharmaceutical Ingredients
erythromycin thiocyanate
erythromycin thiocyanate contract manufacturing
erythromycin thiocyanate contract manufacturing
| Structure |  |
| Molecular | C37H67NO13HCNS |
| Molecular Weight | 793.02 |
| Chemical Name | Erythromycin,thiocyanate (salt);Erythromycin, thiocyanate (salt);(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl], Erythromycin thiocyanate |
| Therapeutic Category | Antibiotic |
| CAS# | 7704-67-8 |
| Packaging | Tight Container |
| Shelf Life | 3 years |
| Specifications | |
| Test Name | Acceptance Criteria |
|---|---|
| Identification (By IR) | Sample and standard spectra are qualitatively identical |
| Loss on Drying | ≤ 10.0 % |
| Thiocyanate | ≥ 5.9 % |
| Appearance | Powder |
| Color | White to buff |
| pH (of 0.1% Water Suspension) | 5.0 - 7.0 |
| Sulphated Ash (EP/BP) / Residue on Ignition (USP) | ≤ 0.5 % |
| Erythromycin Microbiological - “As Is” | mcg/mg |
| Erythromycin Microbiological - Anhydrous | ≥ 750 mcg/mg |
| Ery A + B + C (Anhydrous by HPLC) | ≥ 79.0 % |
| Ery B (Anhydrous by HPLC) | ≤ 4.5 % |
| Ery C (Anhydrous by HPLC) | ≤ 5.0 % |
| Ery E (Anhydrous by HPLC) | ≤ 4.5 % |
| Ery A Enol Ether (Anhydrous by HPLC) | ≤ 1.2 % |
| Largest Unspecified Impurity (Anhydrous by HPLC) | ≤ 1.4 % |
| Solution (10%) in Methanol | Clear to slightly hazy Practically colorless to pale yellow |